Vaccine associated paralytic poliomyelitis cases from children presenting with acute flaccid paralysis in Uganda.
نویسندگان
چکیده
A retrospective study to identify VAPP cases from the entire Uganda was conducted between January 2003 and December 2011. Eleven of the 106 AFP cases were VAPPs. The VAPP rate ranged from 0 to 3.39 cases per 1,000,000 birth cohorts and the peak was in 2009 when there was scaling up of OPV immunization activities following an importation of wild poliovirus in the country. All the subsequent polio suspect cases since then have been vaccine-associated polio cases. Our data support the strategy to withdraw OPV and introduce IPV progressively in order to mitigate against the paralysis arising from Sabin polioviruses.
منابع مشابه
Vaccine-associated paralytic poliomyelitis.
In the wake of the World Health Organization’s (WHO) program to eradicate poliomyelitis globally by the end of the year 2000 (in 1997 only 5,186 cases were reported world-wide), attention has focussed on the importance of good surveillance of acute flaccid paralysis, which is essential for a country to qualify for being declared polio-free, and on the occurrence of vaccine–associated paralytic ...
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ورودعنوان ژورنال:
- Journal of medical virology
دوره 87 12 شماره
صفحات -
تاریخ انتشار 2015